Q-dextran, a product provided as a crude white powder that dissolves easily in water, is made by reacting dextran fractions with 2,3-epoxypropyltrimethylammonium chloride. It contains roughly 2% nitrogen, signifying that there is one quaternary ammonium group for every four glucose units in its composition. Q-dextran is a high-quality product with a molecular weight of 3500-5500 and nitrogen content of 1.5-2.5%.
Molecular Weight
3500-5500
Form
White to off-white powder
Solubility
Q-dextran dissolves readily in water.
Identity
Confirmed by NMR/HPLC/MS.
pH
5.0-7.0
Applications
Q-dextran with the molecular weight of 3500-5500 and nitrogen content of 1.5-2.5% can be used for the study of the responses in cellular systems where the net charge of Q-dextran plays a significant role, including in vaccine adjuvant development.
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