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R8 peptide-modified epirubicin and dihydroartemisinin co-loaded liposomes

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Cat. No.: X26-05-ZQ2912

R8 peptide-modified epirubicin and dihydroartemisinin co-loaded liposomes

Name: R8 peptide-modified epirubicin and dihydroartemisinin co-loaded liposomes
SKU: X26-05-ZQ2912

Inquiry

Synonym: R8-modified epirubicin/DHA co-loaded LPs; R8 peptide-modified epirubicin-dihydroartemisinin liposomes; R8-functionalized epirubicin/DHA co-delivery liposomes

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This highly advanced multi-functional targeted formulation features octa-arginine peptide functionalized liposomes co-loaded with epirubicin and dihydroartemisinin. The complex structural framework encapsulates the hydrophilic anthracycline epirubicin within its central aqueous core via an active remote-loading gradient, while simultaneously incorporating the hydrophobic sesquiterpene lactone compound dihydroartemisinin within the lipophilic tail regions of its bilayer shell, whose exterior boundary is surface-modified with cell-penetrating octa-arginine (R8) peptides linked via covalent polymer anchors. This precise modification coordinates a highly uniform charged cell-penetrating peptide layer with a protective dual-phase multi-cargo boundary, completely preventing drug crystallization, anthracycline leakage, and physical vesicle aggregation across variable laboratory media.

Source

Custom synthesis

Functional Group

R8 peptide; Epirubicin; Dihydroartemisinin

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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