In the raltitrexed-xylan composite, the chemotherapeutic agent's properties are integrated with xylan's β-1,4-xylose architecture derived from lignocellulosic biomass. The carbohydrate matrix serves as an eco-friendly solubility enhancer through its hydrophilic polymer network.
Glycan Name
Xylan
Glycan Structure
Its glycan structure is a linear backbone of β-1,4-linked D-xylose residues with side-chain substitutions including α-linked arabinofuranose, glucuronic acid/4-O-methyl-glucuronic acid, and acetyl groups at O-2 or O-3 positions.
Source
Chemical synthesis
Functional Group
Raltitrexed
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Xylan-raltitrexed can be used for its potential to evaluate antifolate drug retention in 3D multicellular tumor spheroid cultures.
Publications
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Publications
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