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Ras inhibitor ARS-853, Purity ≥98%

Cat. No.: X24-05-ZQ883

Ras inhibitor ARS-853, Purity ≥98%

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Synonym: 1629268-00-3; ARS853; ARS 853; Ras inhibitor

  • CAS Number: 1629268-00-3
  • Compound CID: 86279165
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Product Size
1 mg; 5 mg; 10 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
ARS-853, soluble in warmed DMSO and warmed ethanol and insoluble in water, blocks the activity of Ras proteins, which play a key role in cell signal transduction and are frequently implicated in oncogenic mutations. It targets KRAS(G12C).
Molecular Weight
432.94
Molecular Formula
C22H29ClN4O3
Targets
KRAS(G12C): 2.5 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 80 mg/mL (184.78 mM); Water: Insoluble; Warmed ethanol: 1 mg/mL (2.3 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
ARS-853 can be used to study selective inhibition of KRAS G12C for targeted cancer therapy.
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