GW4064, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting FXR. The molecular weight of the compound is 542.8, and its molecular formula is C28H22Cl3NO4. It targets the FXR (CV1).
Molecular Weight
542.8
Molecular Formula
C28H22Cl3NO4
Targets
FXR (CV1)
Form
Lyophilized powder
Purity
≥98%
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 99 mg/mL (182.37 mM); Water: insoluble; Ethanol: insoluble; In vivo: 0.5% methylcellulose, 10 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
GW4064 can be studied extensively for its potential therapeutic applications in the treatment of liver diseases such as non-alcoholic fatty liver disease (NAFLD) and cholestasis.
Publications
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Publications
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