Cat. No.: X24-09-YM304
Renin-angiotensin-aldosterone system (RAAS) inhibitor, GW4064, Purity ≥98%
Synonym: 278779-30-9; GW-4064; GW 4064; 3-[(E)-2-[2-Chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]ethenyl]benzoic acid; Renin-angiotensin-aldosterone system (RAAS) inhibitor
- MDL: MFCD09971006
- CAS Number: 278779-30-9
- Compound CID: 9893571
Product Size
10 mg; 50 mg; 100 mg; 200 mg
Properties
Description
GW4064, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting FXR. The molecular weight of the compound is 542.8, and its molecular formula is C28H22Cl3NO4. It targets the FXR (CV1).
Molecular Formula
C28H22Cl3NO4
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 99 mg/mL (182.37 mM); Water: insoluble; Ethanol: insoluble; In vivo: 0.5% methylcellulose, 10 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
GW4064 can be studied extensively for its potential therapeutic applications in the treatment of liver diseases such as non-alcoholic fatty liver disease (NAFLD) and cholestasis.
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