Cat. No.: X24-06-ZQ966
Reverse transcriptase inhibitor Dapivirine, Purity ≥98%
Synonym: 244767-67-7; Reverse transcriptase inhibitor; R 147681; TMC 120; TMC 120R147681
- MDL: MFCD09833899
- CAS Number: 244767-67-7
- Compound CID: 214347
Product Size
10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
Dapivirine, soluble in DMSO and insoluble in ethanol and water, obstructs the action of reverse transcriptase, an enzyme crucial for the replication of retroviruses like HIV. It targets HIV reverse transcriptase.
Molecular Formula
C20H19N5
Targets
HIV reverse transcriptase: 24 nM
Solubility
DMSO: 29 mg/mL (88.03 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Dapivirine is utilized to examine its efficacy as a non-nucleoside reverse transcriptase inhibitor in HIV prevention.
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