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RGD and R8 peptide co-modified cisplatin liposomes

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Cat. No.: X26-05-ZQ2340

RGD and R8 peptide co-modified cisplatin liposomes

Name: RGD and R8 peptide co-modified cisplatin liposomes
SKU: X26-05-ZQ2340

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Synonym: RGD/R8 peptide co-modified cisplatin liposomes; RGD-R8 co-modified cisplatin LPs; RGD and R8 dual-peptide functionalized cisplatin liposomes

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This highly complex dual-modified system features cyclic arginylglycylaspartic acid and octaarginine peptide dual-functionalized cisplatin liposomes. The structural framework encapsulates the inorganic square-planar coordination complex cisplatin entirely within its central aqueous reservoir, whose exterior surface is dual-modified with cyclic arginylglycylaspartic acid (RGD) targeting peptides and cell-penetrating octaarginine (R8) peptides linked via polymer-lipid anchors. This multi-component configuration balances a highly dense cationic surface charge density and strong electrostatic repulsive forces with a dense target-mimetic ligand array, completely preventing physical vesicle aggregation while restricting the passive diffusion of the heavy metal cargo.

Source

Custom synthesis

Functional Group

RGD peptide; R8 peptide; Cisplatin

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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