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RGD and TAT co-modified paclitaxel (PTX)-loaded liposomes

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Cat. No.: X26-05-ZQ2827

RGD and TAT co-modified paclitaxel (PTX)-loaded liposomes

Name: RGD and TAT co-modified paclitaxel (PTX)-loaded liposomes
SKU: X26-05-ZQ2827

Inquiry

Synonym: RGD/TAT co-modified PTX-loaded LPs; RGD-TAT co-modified paclitaxel liposomes; RGD/TAT dual-peptide paclitaxel co-delivery liposomes

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This highly advanced multi-functional targeted formulation features arginylglycylaspartic acid and TAT peptide co-modified paclitaxel loaded liposomes. The structural matrix incorporates the highly hydrophobic diterpenoid paclitaxel (PTX) directly within the lipophilic hydrocarbon tail domains of its bilayer shell, whose exterior boundary is dual-modified with specific arginylglycylaspartic acid (RGD) targeting peptides and transactivator of transcription (TAT) cell-penetrating peptides linked via polymer anchors. This complex layout coordinates a dense target-mimetic array and a highly uniform charged cell-penetrating peptide layer with an optimized taxane matrix, completely preventing physical vesicle aggregation while suppressing the rapid crystallization, phase separation, and precipitation of paclitaxel in open laboratory testing media.

Source

Custom synthesis

Functional Group

RGD peptide; TAT peptide; Paclitaxel

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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