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Ribonucleotide reductase inhibitor, Triapine, Purity ≥98%
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Cat. No.: X24-09-YM590

Ribonucleotide reductase inhibitor, Triapine, Purity ≥98%

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Synonym: 200933-27-3; 3-AP; 2-((3-Aminopyridin-2-yl)methylene)hydrazinecarbothioamide; PAN-811; 3-Aminopyridine-2-carboxaldehyde thiosemicarbazone; [(E)-(3-Aminopyridin-2-yl)methylideneamino]thiourea; Ribonucleotide reductase inhibitor

  • MDL: MFCD00924747
  • CAS Number: 200933-27-3
  • Compound CID: 9571836
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Triapine, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting ribonucleotide reductase. The molecular weight of the compound is 195.24, and its molecular formula is C7H9N5S.
Molecular Weight
195.24
Molecular Formula
C7H9N5S
Form
Lyophilized powder
Purity
≥98%
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 17 mg/mL (87.07 mM); Water: insoluble; Ethanol: insoluble; In vivo: 5% DMSO + 40% PEG300 + 5% Tween80 + 50% ddH2O, 1.18 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Triapine plays a key role in disrupting DNA synthesis in rapidly dividing tumor cells.
Publications
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