Riociguat (BAY 63-2521), soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets guanylate cyclase.
Riociguat (BAY 63-2521) can be used to increase levels of cyclic guanosine monophosphate (cGMP), leading to vasodilation and improved blood flow in the lungs.
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