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RS 127445 HCl
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Cat. No.: X23-12-YM1343

RS 127445 HCl

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Synonym: 199864-86-3; 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine hydrochloride

  • CAS Number: 199864-86-3
  • Compound CID: 9905058
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
RS 127445 HCl inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT2A receptor, 5-HT2B receptor, 5-HT2C receptor, 5-HT3 receptor, 5-HT5 receptor, 5-HT6 receptor, and sPLA2.
Molecular Weight
317.79
Molecular Formula
C17H17ClFN3
Targets
5-HT2A receptor: 6.3 (pKi); 5-HT2B receptor: 9.5 (pKi); 5-HT2C receptor: 6.4 (pKi); 5-HT3 receptor: <6 (pKi); 5-HT5 receptor: <6 (pKi); 5-HT6 receptor: <6 (pKi); sPLA2: 5.5 (pKi)
Form
Lyophilized powder
Purity
>98%
Applications
RS 127445 HCl can be used for its ability to reduce pulmonary vascular resistance and improve blood flow in the lungs.
Publications
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