Lentinan-RVG29 peptide, termed RVG29-lentinan, develops a neurotropic conjugate through fusion of rabies virus glycoprotein peptides with lentinan's β-glucan scaffold. This CNS-targeted hybrid preserves helical conformation while enabling brain tumor suppression via thymic immune stimulation.
Glycan Name
Lentinan
Glycan Structure
Its glycan structure is a β-(1→3)-linked d-glucose backbone with β-(1→6)-glucosyl side branches.
Source
Chemical synthesis
Functional Group
RVG29
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Lentinan-RVG29 peptide can be used for its potential to enhance neuronal uptake using RVG29 peptide modifications in blood-brain barrier transport assays.
Publications
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Publications
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