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SB 271046 hydrochloride
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Cat. No.: X23-12-YM563

SB 271046 hydrochloride

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Synonym: 209481-24-3; SB 271046 (Hydrochloride); SB-271046A

  • CAS Number: 209481-24-3
  • Compound CID: 6918455
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
SB 271046 Hydrochloride, soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT1A receptor, 5-HT1B receptor, 5-HT1D receptor, 5-HT1E receptor, 5-HT1F receptor, 5-HT2A receptor, 5-HT2B receptor, 5-HT4 receptor, 5-HT6 receptor, 5-HT7 receptor, and human 5-HT2C receptor.
Molecular Weight
488.45
Molecular Formula
C20H23Cl2N3O3S2
Targets
5-HT1A receptor: 6.35 (pKi); 5-HT1B receptor: 6.05 (pKi); 5-HT1D receptor: 6.55 (pKi); 5-HT1E receptor: <4.99 (pKi); 5-HT1F receptor: 5.95 (pKi); 5-HT2A receptor: 5.62 (pKi); 5-HT2B receptor: 5.41 (pKi); 5-HT4 receptor: 5.27 (pKi); 5-HT6 receptor: 8.92-9.02 (pKi); 5-HT7 receptor: 5.39 (pKi); Human 5-HT2C receptor: 5.73 (pKi)
Form
Lyophilized powder
Purity
>98%
Solubility
DMSO: 38 mg/mL (77.8 mM); Water: insoluble; Ethanol: insoluble
Applications
SB 271046 Hydrochloride can be used to research and develop therapeutic strategies for certain diseases that involve excessive activation of GPCR-G protein signaling pathways.
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