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Cat. No.: X23-10-ZQ682

SIK inhibitor ARN-3236, Purity ≥98%

Synonym: 1613710-01-2; ARN-3236; 3-(2,4-dimethoxyphenyl)-4-(thiophen-3-yl)-1H-pyrrolo[2,3-b]pyridine; CHEMBL4539742; 3-(2,4-Dimethoxyphenyl)-4-(3-thienyl)-1H-pyrrolo[2,3-b]pyridine; 3-(2,4-Dimethoxyphenyl)-4-thiophen-3-yl-1H-pyrrolo[2,3-b]pyridine; SIK inhibitor

  • MDL: MFCD31813721
  • CAS Number: 1613710-01-2
  • Compound CID: 74766530
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Product Size
2 mg; 5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
MSDS
Properties
Description
ARN-3236, soluble in DMSO and ethanol and insoluble in water, is a potential salt-inducible kinase (SIK) inhibitor. It targets SIK1, SIK2, and SIK3.
Molecular Weight
336.4
Molecular Formula
C19H16N2O2S
Targets
SIK1: 21.63 nM; SIK2: <1 nM; SIK3: 6.63 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 62 mg/mL (184.3 mM); Water: Insoluble; Ethanol: 2 mg/mL (5.94 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
ARN-3236 can be used to investigate its role as an inhibitor of p300/CBP, relevant in cancer and epigenetic regulation.
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