Properties
Description
Silodosin (rapaflo), soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets α1-adrenergic receptor.
Molecular Formula
C25H32F3N3O4
Targets
α1-Adrenergic receptor
Solubility
DMSO: 97 mg/mL (195.74 mM); Water: insoluble; Ethanol: 97 mg/mL (195.74 mM)
Applications
Silodosin (rapaflo) can be used for its effect on selectively blocking alpha-1 adrenergic receptors in the prostate gland, leading to relaxation of smooth muscle tissue in the prostate and the bladder neck, which helps improve urinary flow and reduce symptoms of obstruction.
