GNE-616 blocks sodium channels, affecting the action potential propagation in neurons and muscle cells, crucial for neurological and muscular function. It targets hNav1.7 and hNav1.7.
Molecular Weight
537.53
Molecular Formula
C24H23F4N5O3S
Targets
hNav1.7: 0.79 nM (Ki); hNav1.7: 0.38 nM (Kd)
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
GNE-616 is a sodium channel inhibitor used in research on cardiac arrhythmias to explore its potential in stabilizing heart rhythm.
Publications
Publications (0)
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Publications
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