Sodium dichloroacetate, a specific inhibitor of pyruvate dehydrogenase kinase (PDK), has been shown to derepress Na+-K+-2Cl- cotransporter and a mitochondrial potassium-ion channel axis. Sodium dichloroacetate increases reactive oxygen species (ROS) generation, triggers apoptosis in cancer cells, and inhibits tumor growth. This product can be used in the research of anticancer drugs.
Molecular Weight
150.918
Molecular Formula
C2HCl2NaO2
Form
White powder
Purity
≥98%
Identity
Confirmed by MS and NMR.
Melting Point
198°C
Applications
Sodium dichloroacetate can be used in the research of anticancer drugs.
Safety Information
Personal Protective Equipment
Gloves, eyeshields, N95 mask
Publications
Publications (0)
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Publications
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