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Cat. No.: X24-06-ZQ825

SphK inhibitor SKI-II, Purity ≥98%

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Synonym: 312636-16-1; SphK inhibitor; SKI II; Sphingosine kinase inhibitor II

  • MDL: MFCD00733553
  • CAS Number: 312636-16-1
  • Compound CID: 753704
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Product Size
10 mg; 25 mg; 100 mg; 200 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
SKI-II, soluble in DMSO and ethanol and insoluble in water, targets and inhibits the activity of sphingosine kinase enzymes, which play a crucial role in the sphingolipid metabolic pathway. It targets S1P receptor.
Molecular Weight
302.78
Molecular Formula
C15H11ClN2OS
Targets
S1P receptor: 0.5 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 57 mg/mL (188.25 mM); Water: Insoluble; Ethanol: 57 mg/mL (188.25 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
SKI-II is used as a non-specific SphK inhibitor to study sphingolipid metabolism and its impact on cancer cell viability and drug resistance.
Publications
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