Src inhibitor PP1, Purity ≥98%

Synonym: 172889-26-8; Src inhibitor; PP-1; PP 1

MDL: MFCD01076570
CAS Number: 172889-26-8
Compound CID: 1400

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

PP1, soluble in DMSO and insoluble in ethanol and water, blocks the activity of Src kinases, which are involved in various cellular processes such as growth, differentiation, and survival, and have been implicated in the progression of several cancers and other diseases. It targets Fyn, Kit, Bcr-Abl, EGFR, JAK2, lck, and ZAP70.

Molecular Weight

281.36

Molecular Formula

C₁₆H₁₉N₅

Targets

Fyn: 6 nM; Kit: 75 nM; Bcr-Abl: 1 nM; EGFR: 250 nM; JAK2: >50 μM; lck: 5 nM; ZAP70: >100 μM

Form

Lyophilized powder

Purity

Solubility

DMSO: 212391-63-4; Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

PP1 is a foundational compound used to study Src kinase inhibition, valuable in cancer research for targeting signal transduction mechanisms.