Cat. No.: X24-06-ZQ347
Src inhibitor PP1, Purity ≥98%
Synonym: 172889-26-8; Src inhibitor; PP-1; PP 1
- MDL: MFCD01076570
- CAS Number: 172889-26-8
- Compound CID: 1400
Product Size
10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
PP1, soluble in DMSO and insoluble in ethanol and water, blocks the activity of Src kinases, which are involved in various cellular processes such as growth, differentiation, and survival, and have been implicated in the progression of several cancers and other diseases. It targets Fyn, Kit, Bcr-Abl, EGFR, JAK2, lck, and ZAP70.
Molecular Formula
C16H19N5
Targets
Fyn: 6 nM; Kit: 75 nM; Bcr-Abl: 1 nM; EGFR: 250 nM; JAK2: >50 μM; lck: 5 nM; ZAP70: >100 μM
Solubility
DMSO: 212391-63-4; Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
PP1 is a foundational compound used to study Src kinase inhibition, valuable in cancer research for targeting signal transduction mechanisms.
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