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Cat. No.: X24-06-ZQ349

Src inhibitor PP2, Purity ≥98%

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Synonym: 172889-27-9; Src inhibitor; PP-2; PP 2

  • CAS Number: 172889-27-9
  • Compound CID: 4878
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
PP2, soluble in DMSO and ethanol and insoluble in water, blocks the activity of Src kinases, which are involved in various cellular processes such as growth, differentiation, and survival, and have been implicated in the progression of several cancers and other diseases. It targets EGFR, Fyn, and JAK2.
Molecular Weight
301.78
Molecular Formula
C15H16ClN5
Targets
EGFR: 480 nM; Fyn: 5 nM; JAK2: >50 μM; LCK: 4 nM; ZAP70: >100 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 52 mg/mL (172.31 mM); Water: Insoluble; Ethanol: 2 mg/mL (6.62 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
PP2 is applied in research to inhibit Src-family kinases, thereby helping scientists study signal transduction pathways involved in cell growth and cancer progression.
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