Src inhibitor PP2, Purity ≥98%

Synonym: 172889-27-9; Src inhibitor; PP-2; PP 2

CAS Number: 172889-27-9
Compound CID: 4878

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

PP2, soluble in DMSO and ethanol and insoluble in water, blocks the activity of Src kinases, which are involved in various cellular processes such as growth, differentiation, and survival, and have been implicated in the progression of several cancers and other diseases. It targets EGFR, Fyn, and JAK2.

Molecular Weight

301.78

Molecular Formula

C₁₅H₁₆ClN₅

Targets

EGFR: 480 nM; Fyn: 5 nM; JAK2: >50 μM; LCK: 4 nM; ZAP70: >100 μM

Form

Lyophilized powder

Purity

Solubility

DMSO: 52 mg/mL (172.31 mM); Water: Insoluble; Ethanol: 2 mg/mL (6.62 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

PP2 is applied in research to inhibit Src-family kinases, thereby helping scientists study signal transduction pathways involved in cell growth and cancer progression.