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Survivin-siRNA and osthole co-loaded cationic liposomal nanoparticles
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Cat. No.: X26-05-ZQ2057

Survivin-siRNA and osthole co-loaded cationic liposomal nanoparticles

Synonym: Survivin-siRNA/osthole co-loaded cationic LPs; Survivin-siRNA and osthole co-delivery cationic NLs; Survivin-siRNA/osthole cationic lipopolyplexes

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Properties
Description
This highly complex dual-cargo formulation features survivin small interfering RNA and osthole co-loaded cationic liposomal nanoparticles. The structural framework incorporates a combined hydrophobic and hydrophilic regimen, embedding the lipophilic coumarin derivative osthole directly within the hydrocarbon tail core of a phospholipid bilayer while electrostatically condensing survivin-targeted small interfering RNA (siRNA) fragments onto its cationic lipid surface. This advanced multi-loading configuration coordinates the positive charge density of the headgroups to protect the nucleic acid strands from premature degradation, while preventing competitive phase separation of the coumarin cargo in open laboratory media.
Source
Custom synthesis
Functional Group
Survivin-siRNA; Osthole; Cationic lipid
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
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