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Syk inhibitor Fostamatinib, Purity ≥98%

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Cat. No.: X24-06-ZQ520

Syk inhibitor Fostamatinib, Purity ≥98%

Synonym: 901119-35-5; Syk inhibitor; R-788

MDL: MFCD16628163
CAS Number: 901119-35-5
Compound CID: 11671467

Product Size

2 mg; 5 mg; 10 mg; 25 mg

Price

Datasheet

MSDS

Properties

Description

Fostamatinib, soluble in DMSO and insoluble in ethanol and water, blocks the activity of spleen tyrosine kinase (Syk), a key protein involved in the signaling pathways of various immune cells and implicated in the pathogenesis of autoimmune diseases and certain cancers. It targets adenosine A3 receptor, adenosine transporter, monoamine transporter, and Syk.

Molecular Weight

580.5

Molecular Formula

C₂₃H₂₆FN₆O₉P

Targets

Adenosine A3 receptor: 81 nM; Adenosine transporter: 1.84 μM; Monoamine transporter: 2.74 μM; Syk: 41 nM

Form

Lyophilized powder

Purity

Solubility

DMSO: 107 mg/mL (184.34 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Fostamatinib (also known as R935788) is studied for inhibiting Syk kinase in the context of autoimmune disorders and platelet function.

Publications

Publications (0)

Publications

Publications

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