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TCO agent, Chondroitin sulfate-PEG-trans-cyclooctene, Purity ≥95%

Cat. No.: X25-05-YM210

TCO agent, Chondroitin sulfate-PEG-trans-cyclooctene, Purity ≥95%

Synonym: Trans-cyclooctene-PEG-chondroitin sulfate; TCO-PEG-chondroitin sulfate; Chondroitin sulfate-PEG-TCO

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Sub Cat. No. Molecular Weight Glycan Name Functional Group Inquiry
X25-05-YM210-1 PEG 350 Da Chondroitin sulfate TCO Inquiry
X25-05-YM210-2 PEG 550 Da Chondroitin sulfate TCO Inquiry
X25-05-YM210-3 PEG 750 Da Chondroitin sulfate TCO Inquiry
X25-05-YM210-4 PEG 1 kDa Chondroitin sulfate TCO Inquiry
X25-05-YM210-5 PEG 2 kDa Chondroitin sulfate TCO Inquiry
X25-05-YM210-6 PEG 3 kDa Chondroitin sulfate TCO Inquiry
X25-05-YM210-7 PEG 4 kDa Chondroitin sulfate TCO Inquiry
X25-05-YM210-8 PEG 5 kDa Chondroitin sulfate TCO Inquiry
X25-05-YM210-9 PEG 10 kDa Chondroitin sulfate TCO Inquiry
X25-05-YM210-10 PEG 20 kDa Chondroitin sulfate TCO Inquiry
Properties
Description
TCO-modified PEG-chondroitin sulfate (TCO-PEG-CS) installs strained alkenes via PEG-tetrazine conjugation, facilitating rapid tetrazine ligation for modular assembly.
Glycan Structure
The glycan structure of chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) composed of repeating disaccharide units. Each unit consists of: N-acetyl-D-galactosamine (GalNAc) (β1→4 linked) D-glucuronic acid (GlcA) (β1→3 linked)
Source
Chemical synthesis
Functional Group
TCO
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Chondroitin sulfate-PEG-trans-cyclooctene can be used for its potential to advance strain-promoted click chemistry for non-cytotoxic cell surface labeling.
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