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TNF-α inhibitor EVP4593, Purity ≥98%
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Cat. No.: X23-10-ZQ104

TNF-α inhibitor EVP4593, Purity ≥98%

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Synonym: 545380-34-5; QNZ; EVP4593; QNZ (EVP4593); 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline; N4-(4-Phenoxyphenethyl)quinazoline-4,6-diamine; 4-N-[2-(4-Phenoxyphenyl)ethyl]quinazoline-4,6-diamine; TNF-α inhibitor

  • MDL: MFCD06411436
  • CAS Number: 545380-34-5
  • Compound CID: 509554
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
EVP4593, soluble in warmed DMSO and insoluble in water and ethanol, is a compound that reduces inflammation by modulating apoptosis. It targets TNF-α (Jurkat T cells) and NF-κB (Jurkat T cells).
Molecular Weight
356.4
Targets
TNF-α (Jurkat T cells): 7 nM; NF-κB (Jurkat T cells): 11 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 5 mg/mL (14.02 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
EVP4593 can be explored for its role as an inhibitor of neuroprotective pathways and potential therapeutic application in neurodegenerative diseases.
Publications
Publications (0)

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