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Toll-like receptor agonist VTX-2337, Purity ≥98%
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Cat. No.: X23-10-ZQ563

Toll-like receptor agonist VTX-2337, Purity ≥98%

Synonym: Motolimod; 926927-61-9; VTX-2337; Motolimod (VTX-2337); VTX-378; VTX 2337; 2-Amino-N,N-dipropyl-8-(4-(pyrrolidine-1-carbonyl)phenyl)-3H-benzo[b]azepine-4-carboxamide; Toll-like receptor agonist

  • MDL: MFCD28044318
  • CAS Number: 926927-61-9
  • Compound CID: 16049404
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
VTX-2337, soluble in warmed DMSO and ethanol and insoluble in water, is a potent and selective active small molecule agonist of a Toll-like receptor. It targets TLR8.
Molecular Weight
458.6
Molecular Formula
C28H34N4O2
Targets
TLR8: 100 nM (EC50)
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 48 mg/mL (104.67 mM); Water: Insoluble; Ethanol: 13 mg/mL (28.34 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
VTX-2337 can be used to study its role as an immune system modulator via TLR8 activation.
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