Cat. No.: X22-05-ZQ073
Topotecan hydrochloride
Synonym: 119413-54-6; topotecan hydrochloride; Topotecan HCL; (19S)-8-[(Dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione hydrochloride
- MDL: MFCD00866235
- CAS Number: 119413-54-6
- Compound CID: 60699
Product Size
20 mg; 50 mg; 100 mg; 200 mg
Properties
Description
Topotecan hydrochloride is a DNA topoisomerase I inhibitor and induces rapid apoptotic death in human B-lineage acute lymphoblastic leukemia (ALL) cells. It improves survival in three mouse models of poor prognosis ALL and downregulates B-Myb and MycN expression in neuroblastoma cells. This product can be used as a precursor research for pharmaceuticals and personal care products.
Molecular Formula
C23H24ClN3O5
Purity
≥98%, determined by HPLC.
Stability
The product is stable for two years when stored at the recommended temperature.
Identity
Confirmed by MS and NMR.
Applications
Topotecan hydrochloride can be used as a precursor research for pharmaceuticals and personal care products.
Storage
Store at 4°C. Protect from light.
Safety Information
Personal Protective Equipment
Gloves, eyeshields, N95 mask
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