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Topotecan hydrochloride liposomes
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Cat. No.: X26-05-ZQ1551

Topotecan hydrochloride liposomes

Synonym: Topotecan hydrochloride LPs; Topotecan HCl liposomes; Topotecan hydrochloride liposomal nanoparticles

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Properties
Description
This formulation provides topotecan hydrochloride liposomes configured to encapsulate a water-soluble camptothecin derivative within a stable bilayer framework. The structural matrix encapsulates the hydrophilic compound topotecan hydrochloride within its internal aqueous core using a transmembrane ion gradient, which restricts passive drug leakage across the lipid membrane. This configuration shields the delicate lactone ring of the camptothecin structure from rapid chemical hydrolysis and conversion to its inactive carboxylate form in open laboratory media. The resulting vesicles exhibit high colloidal stability, a highly uniform spherical morphology, and a narrow size distribution profile.
Source
Custom synthesis
Functional Group
Topotecan hydrochloride
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
Publications (0)

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