Properties
Description
TPEN, soluble in DMSO and ethanol and insoluble in water, is a heavy metal chelator. The molecular weight of the compound is 424.54, and its molecular formula is C26H28N6.
Molecular Formula
C26H28N6
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 77 mg/mL (181.37 mM); Water: insoluble; Ethanol: 77 mg/mL (181.37 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
TPEN plays a key role in inhibiting zinc-dependent enzymes and processes in cells, including metalloproteinases and various signaling pathways dependent on zinc homeostasis, which can influence cell proliferation and apoptosis.