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TPGS-emulsified paclitaxel-PEG-PLGA nanoparticles

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Cat. No.: X26-05-ZQ2384

TPGS-emulsified paclitaxel-PEG-PLGA nanoparticles

Name: TPGS-emulsified paclitaxel-PEG-PLGA nanoparticles
SKU: X26-05-ZQ2384

Inquiry

Synonym: TPGS-emulsified PTX-PEG-PLGA nanoparticles; TPGS-paclitaxel-PEG-PLGA NPs; TPGS-stabilized PTX-PEG-PLGA nanoparticles

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This advanced engineered non-vesicular formulation features d-alpha-tocopheryl polyethylene glycol 1000 succinate stabilized paclitaxel loaded polymer nanoparticles (TPGS-emulsified paclitaxel-PEG-PLGA nanoparticles). The solid-core architecture consists of a rigid, self-assembled block copolymer matrix of polyethylene glycol and poly(lactic-co-glycolic acid) (PEG-PLGA) encapsulating the highly hydrophobic diterpenoid paclitaxel, emulsified and stabilized by an outer surfactant layer of d-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS). This rigid solid-core configuration completely immobilizes the diterpenoid within the solid polymer matrix, preventing rapid cargo leakage and shielding the active core from premature crystallization or precipitation in open laboratory media.

Source

Custom synthesis

Functional Group

TPGS; Paclitaxel-PLGA polymer matrix

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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