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Triptolide (3-carboxypropyl)triphenylphosphonium bromide-polyethylene glycol-b-polycaprolactone liposomes (TPP-PEG-PCL)
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Cat. No.: X26-05-ZQ1675

Triptolide (3-carboxypropyl)triphenylphosphonium bromide-polyethylene glycol-b-polycaprolactone liposomes (TPP-PEG-PCL)

Synonym: TPP-PEG-PCL triptolide liposomes; TPP-PEG-PCL modified TP liposomes; TPP-PEG-PCL

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Properties
Description
This highly specialized system comprises triptolide-loaded (3-carboxypropyl)triphenylphosphonium bromide-polyethylene glycol-b-polycaprolactone copolymer-lipid hybrid liposomes (TPP-PEG-PCL). The complex matrix incorporates the hydrophobic diterpenoid trioxide triptolide within the lipophilic tail region of a phospholipid bilayer blended with (3-carboxypropyl)triphenylphosphonium bromide-polyethylene glycol-b-polycaprolactone (TPP-PEG-PCL) amphiphilic block copolymers. This advanced surface modification introduces a robust positive surface charge profile derived from the triphenylphosphonium (TPP) cation anchors paired with a protective hydrophilic steric layer. The surrounding lipid-copolymer shell isolates the active core while providing a precise model for studying polymer-lipid hybrid aggregation parameters and sustained-release transport kinetics.
Source
Custom synthesis
Functional Group
TPP; PCL; Triptolide
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
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