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Ultrasound-mediated iRGD-targeted drug-loaded liposome-microbubble complexes (iRGD-LMC)

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Cat. No.: X26-05-ZQ2882

Ultrasound-mediated iRGD-targeted drug-loaded liposome-microbubble complexes (iRGD-LMC)

Name: Ultrasound-mediated iRGD-targeted drug-loaded liposome-microbubble complexes (iRGD-LMC)
SKU: X26-05-ZQ2882

Inquiry

Synonym: iRGD-LMC; Ultrasound-mediated iRGD targeted drug LP-MB complexes; Ultrasound iRGD-targeted drug liposome-microbubble complexes

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This highly advanced complex multi-phase hybrid system features internalizing arginylglycylaspartic acid peptide functionalized and drug-loaded liposome-microbubble assemblies optimized for acoustic triggering (iRGD-LMC). The intricate macromolecular architecture consists of high-purity drug-encapsulated liposome vesicles electrostatically or covalently bound to the outer lipid or protein shell of a gas-filled microbubble template, whose outermost boundary presents specific internalizing arginylglycylaspartic acid (iRGD) targeting peptides. Under baseline laboratory conditions, the macrovesicular assembly remains highly stable; however, exposure to a specific ultrasound acoustic field trigger induces immediate microbubble cavitation and mechanical resonance, causing rapid membrane disruption, altered fluid mechanics, and instantaneous cargo mass transport.

Source

Custom synthesis

Functional Group

iRGD peptide; Active drug; Acoustic gas-core microbubble

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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