Cat. No.: X23-10-ZQ500
VDA inhibitor DMXAA, Purity ≥98%
Synonym: Vadimezan; DMXAA; 117570-53-3; 5,6-Mexaa; 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid; 5,6-Dimethylxantheonone-4-acetic acid; AS-1404; ASA404; VDA inhibitor
- MDL: MFCD00870555
- CAS Number: 117570-53-3
- Compound CID: 123964
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
DMXAA, soluble in DMSO and insoluble in ethanol and water, promptly disrupts the tumor's vascular network, leading to the death of tumor cells reliant on these blood vessels. It targets DT-diaphorase and DT diaphorase.
Molecular Formula
C17H14O4
Targets
DT-diaphorase: 20 μM (Ki); DT diaphorase: 20 μM (Ki)
Solubility
DMSO: 7 mg/mL (24.79 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
DMXAA can be used to study its anti-tumor properties and its role in cancer therapy as an antivascular agent.
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