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VU 0364770
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Cat. No.: X23-12-YM630

VU 0364770

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Synonym: 61350-00-3; N-(3-chlorophenyl)picolinamide

  • CAS Number: 61350-00-3
  • Compound CID: 836002
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Product Size
25 mg; 50 mg; 100 mg; 500 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
VU 0364770, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets human mGlu4, mGlu5, mGlu6, and rat mGlu4.
Molecular Weight
232.67
Molecular Formula
C12H9ClN2O
Targets
Human mGlu4: 1.1 μM (EC50); mGlu5: 17.9 μM (EC50); mGlu6: 6.8 μM (EC50); Rat mGlu4: 290 nM (EC50)
Form
Lyophilized powder
Purity
>98%
Solubility
DMSO: 46 mg/mL (197.7 mM); Water: insoluble; Ethanol: 46 mg/mL (197.7 mM)
Applications
VU 0364770 can be used for its ability to enhance the activity of the mGluR5 receptor, which may lead to improved cognitive function and behavioral outcomes.
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