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WGA-modified daunorubicin/tetrandrine co-loaded liposomes (WGA-DNR-TET)
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Cat. No.: X26-05-ZQ2843

WGA-modified daunorubicin/tetrandrine co-loaded liposomes (WGA-DNR-TET)

Synonym: WGA-DNR-TET; WGA-modified daunorubicin-tetrandrine co-loaded LPs; WGA-functionalized daunorubicin/tetrandrine co-delivery liposomes

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Properties
Description
This highly advanced multi-functional targeted formulation features wheat germ agglutinin functionalized liposomes co-loaded with daunorubicin and tetrandrine (WGA-DNR-TET). The complex structural framework encapsulates the hydrophilic anthracycline daunorubicin (DNR) within its central aqueous core while simultaneously incorporating the hydrophobic bisbenzylisoquinoline alkaloid tetrandrine (TET) within the lipophilic tail regions of its bilayer shell, whose exterior boundary is surface-modified with macromolecular wheat germ agglutinin (WGA) lectin proteins linked via covalent anchors. This intricate configuration coordinates a dense target-mimetic carbohydrate-binding protein array with a protective dual-phase multi-cargo boundary, completely preventing alkaloid crystallization, anthracycline leakage, and physical vesicle aggregation under ambient laboratory testing conditions.
Source
Custom synthesis
Functional Group
Wheat germ agglutinin (WGA); Daunorubicin; Tetrandrine
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
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