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Cat. No.: X24-07-ZQ198
Wnt inhibitor IWR-1-endo, Purity ≥98%
Synonym: 1127442-82-3; Wnt inhibitor
- MDL: MFCD18086875
- CAS Number: 1127442-82-3
- Compound CID: 44483163
Properties
Description
IWR-1-endo, soluble in DMSO and insoluble in ethanol and water, is a compound that interferes with the Wnt signaling pathway, which plays a key role in regulating cell proliferation, migration, and differentiation. It targets Wnt (L-cells expressing Wnt3A).
Molecular Weight
409.44
Molecular Formula
C25H19N3O3
Targets
Wnt (L-cells expressing Wnt3A): 180 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 19 mg/mL (46.4 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
IWR-1-endo is studied for its inhibitory activity on the Wnt/β-catenin signaling pathway, with implications in cancer research.
Publications
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