Properties
Description
5'-O-DMTr-dG(iBu) PACE is a deoxyguanine (dG) derivative with a dimethylphenyl (DMTr) protecting group at the 5' end and an isobutyl (iBu) substituent attached to the side chain.
Molecular Formula
C48H60N7O9P
Form
White to pale yellow solid
Purity
≥98%, determined by HPLC.
Applications
5'-O-DMTr-dG(iBu) PACE is mainly used to synthesize nucleic acid molecules with specific structures, e.g. antisense oligonucleotides or siRNAs (small interfering RNAs) for research and therapeutic use.