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Bcr-Abl inhibitor BMS-354825, Purity ≥98%
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Cat. No.: X24-06-ZQ331

Bcr-Abl inhibitor BMS-354825, Purity ≥98%

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Synonym: 302962-49-8; Bcr-Abl inhibitor

  • MDL: MFCD11046566
  • CAS Number: 302962-49-8
  • Compound CID: 3062316
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Product Size
100 mg; 200 mg; 500 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
BMS-354825, soluble in DMSO and insoluble in ethanol and water, specifically inhibits the activity of the Bcr-Abl tyrosine kinase. It targets Abl, c-Kit (D816V), c-Kit (wt), and Src.
Molecular Weight
488
Molecular Formula
C22H26ClN7O2S
Targets
Abl: 0.6 nM; c-Kit (D816V): 37 nM; c-Kit (wt): 79 nM; Src: 0.8 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 84 mg/mL (172.12 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
BMS-354825, known as dasatinib, inhibits Bcr-Abl and Src kinases in research focused on CML and other cancers.
Publications
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