Cat. No.: X23-12-YM499
Bosentan
Synonym: 147536-97-8; Tracleer; Actelion
- CAS Number: 147536-97-8
- PubChem CID: 104865
Product Size
25 mg; 50 mg; 100 mg; 200 mg
Properties
Description
Bosentan inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets ET-A, and ET-B.
Molecular Formula
C27H29N5O6S
Targets
ET-A: 4.7 nM (Ki); ET-B: 95 nM (Ki)
Applications
Bosentan can be used to helps improve exercise capacity and delay disease progression in patients with PAH.
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