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BTK inhibitor ACP-196, Purity ≥98%
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Cat. No.: X24-06-ZQ413

BTK inhibitor ACP-196, Purity ≥98%

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Synonym: 1420477-60-6; BTK inhibitor; Acalabrutinib; ACP196; ACP 196

  • MDL: MFCD29472294
  • CAS Number: 1420477-60-6
  • Compound CID: 71226662
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
ACP-196, soluble in DMSO and ethanol and insoluble in water, is a compound designed to block Bruton’s tyrosine kinase (BTK), an enzyme essential for the proliferation and survival of certain cancerous B cells. It targets BTK.
Molecular Weight
465.52
Molecular Formula
C26H23N7O2
Targets
BTK: 3 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 80 mg/mL (171.85 mM); Water: Insoluble; Ethanol: 80 mg/mL (171.85 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
ACP-196 (Acalabrutinib) is used to study B-cell receptor pathway disruption in the treatment of chronic lymphocytic leukemia (CLL) and other B-cell malignancies.
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