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CFTR inhibitor VX-661, Purity ≥98%
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Cat. No.: X24-07-ZQ358

CFTR inhibitor VX-661, Purity ≥98%

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Synonym: 1152311-62-0; CFTR inhibitor; VX661; VX 661

  • MDL: MFCD23106064
  • CAS Number: 1152311-62-0
  • Compound CID: 46199646
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
VX-661, soluble in DMSO and insoluble in ethanol and water, blocks the activity of the cystic fibrosis transmembrane conductance regulator protein, which plays a crucial role in the movement of chloride ions across cell membranes. It targets F508del-CFTR.
Molecular Weight
520.5
Molecular Formula
C26H27F3N2O6
Targets
F508del-CFTR
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 95 mg/mL (182.51 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
VX-661 is a CFTR modulator investigated for its potential to improve chloride transport in diseases like cystic fibrosis.
Publications
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