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CSF-1R inhibitor BLZ945, Purity ≥98%

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Cat. No.: X24-06-ZQ396

CSF-1R inhibitor BLZ945, Purity ≥98%

Synonym: 953769-46-5; CSF-1R inhibitor; BLZ 945; BLZ-945

MDL: MFCD28142668
CAS Number: 953769-46-5
Compound CID: 46184986

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

BLZ945, soluble in DMSO and warmed ethanol and insoluble in water, inhibits the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), interfering with pathways leading to cell growth and metastasis. It targets CSF-1R.

Molecular Weight

398.4

Molecular Formula

C₂₀H₂₂N₄O₃S

Targets

CSF-1R: 1 nM

Form

Lyophilized powder

Purity

Solubility

DMSO: 77 mg/mL (193.23 mM); Water: Insoluble; Warmed ethanol: 3 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

BLZ945 is used to investigate macrophage-related mechanisms in cancer and inflammatory research, highlighting its therapeutic potential.

Publications

Publications (0)

Publications

Publications

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