Cat. No.: X24-06-ZQ396
CSF-1R inhibitor BLZ945, Purity ≥98%
Synonym: 953769-46-5; CSF-1R inhibitor; BLZ 945; BLZ-945
- MDL: MFCD28142668
- CAS Number: 953769-46-5
- Compound CID: 46184986
Product Size
10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
BLZ945, soluble in DMSO and warmed ethanol and insoluble in water, inhibits the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), interfering with pathways leading to cell growth and metastasis. It targets CSF-1R.
Molecular Formula
C20H22N4O3S
Solubility
DMSO: 77 mg/mL (193.23 mM); Water: Insoluble; Warmed ethanol: 3 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
BLZ945 is used to investigate macrophage-related mechanisms in cancer and inflammatory research, highlighting its therapeutic potential.
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