Cat. No.: X24-06-ZQ392
CSF-1R inhibitor GW2580, Purity ≥98%
Synonym: 870483-87-7; CSF-1R inhibitor; GW 2580; GW-2580
- MDL: MFCD12024701
- CAS Number: 870483-87-7
- Compound CID: 11617559
Product Size
25 mg; 50 mg; 100 mg; 200 mg
Properties
Description
GW2580, soluble in DMSO and insoluble in ethanol and water, inhibits the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), interfering with pathways leading to cell growth and metastasis.
Molecular Formula
C20H22N4O3
Solubility
DMSO: 48 mg/mL (131 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
GW2580 is used to inhibit CSF-1R in macrophage studies, which aids in understanding its role in cancer and inflammatory diseases.
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