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Dextran-doxorubicin prodrug polymeric nanoparticles
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Cat. No.: X26-06-ZQ5651

Dextran-doxorubicin prodrug polymeric nanoparticles

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Synonym: Dextran-Dox prodrug nanoparticles; Dextran-doxorubicin prodrug polymeric nanoparticles; Glucan-anthracycline macromolecular conjugate grains; Dextran doxorubicin prodrug polymeric; Dextran-Dox prodrug tumor-targeted nodes

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Polymer nanoparticles assembled from dextran backbones covalently linked to doxorubicin (Dox) molecules via a pH-sensitive hydrazone or ester linker. The covalent bond remains intact at physiological blood pH (7.4) and undergoes hydrolytic cleavage within acidic endosomal compartments (pH5.5).
Source
Custom synthesis
Functional Group
Dextran; Doxorubicin
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Applications
pH-triggered intracellular chemotherapeutic delivery, long-circulating macromolecular prodrug profiles, and reduction of systemic side effects.
Publications
Publications (0)

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