Cat. No.: X24-08-YM101
DNA-RNA synthesis inhibitor, 4EGI-1, Purity ≥98%
Synonym: 315706-13-9; 4EGI1; 4EGI 1; (2E-2-[[4-(3,4-Dichlorophenyl)-1,3-thiazol-2-yl]hydrazinylidene]-3-(2-nitrophenyl)propanoic acid
- MDL: MFCD02330020
- CAS Number: 315706-13-9
- Compound CID: 5717952
Product Size
10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
4EGI-1, soluble in DMSO and insoluble in water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting DNA-RNA synthesis. It targets the eIF4E/eIF4G.
Molecular Formula
C18H12Cl2N4O4S
Targets
eIF4E/eIF4G: 25 μM (Kd)
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 79 mg/mL (175.06 mM); Water: insoluble; Ethanol: insoluble; In vivo: 5% DMSO + pbs, 3 mg/mL
Applications
4EGI-1 is a DNA damage inhibitor that plays a key role in the initiation of translation in eukaryotic cells.
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