4EGI-1, soluble in DMSO and insoluble in water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting DNA-RNA synthesis. It targets the eIF4E/eIF4G.
Molecular Weight
451.28
Molecular Formula
C18H12Cl2N4O4S
Targets
eIF4E/eIF4G: 25 μM (Kd)
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 79 mg/mL (175.06 mM); Water: insoluble; Ethanol: insoluble; In vivo: 5% DMSO + pbs, 3 mg/mL
Applications
4EGI-1 is a DNA damage inhibitor that plays a key role in the initiation of translation in eukaryotic cells.
Publications
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Publications
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