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DNMT inhibitor O6-Benzylguanine, Purity ≥98%
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Cat. No.: X24-05-ZQ557

DNMT inhibitor O6-Benzylguanine, Purity ≥98%

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Synonym: 19916-73-5; CCRIS 9383; DNA methyltransferase inhibitor

  • CAS Number: 19916-73-5
  • Compound CID: 4578
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Product Size
50 mg; 100 mg; 500 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
O6-Benzylguanine, soluble in DMSO and ethanol and insoluble in water, blocks the addition of methyl groups to DNA by methyltransferases, impacting gene expression and genome stability.
Molecular Weight
241.25
Molecular Formula
C12H11N5O
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 41 mg/mL (169.95 mM); Water: Insoluble; Ethanol: 10 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
O6-Benzylguanine can be used to inhibit MGMT, increasing the sensitivity of tumor cells to alkylating chemotherapy drugs.
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