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DNMT inhibitor SGI 1027, Purity ≥98%
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Cat. No.: X24-05-ZQ562

DNMT inhibitor SGI 1027, Purity ≥98%

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Synonym: 1020149-73-8; SGI-1027; SGI1027; DNA methyltransferase inhibitor

  • CAS Number: 1020149-73-8
  • Compound CID: 24858111
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Product Size
10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
SGI 1027, soluble in DMSO and insoluble in ethanol and water, blocks the addition of methyl groups to DNA by methyltransferases, impacting gene expression and genome stability. It targets DNMT1, DNMT3A, and DNMT3B.
Molecular Weight
461.52
Molecular Formula
C27H23N7O
Targets
DNMT1: 6 μM; DNMT3A: 8 μM; DNMT3B: 7.5 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 85 mg/mL (184.17 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
SGI 1027 can be used to inhibit DNA methyltransferases for epigenetic studies.
Publications
Publications (0)

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