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EGFR-HER2 inhibitor AG-494, Purity ≥98%

Cat. No.: X24-05-ZQ672

EGFR-HER2 inhibitor AG-494, Purity ≥98%

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Synonym: 133550-35-3; Tyrphostin AG-494; AG494; AG 494; EGFR-HER2 inhibitor

  • CAS Number: 133550-35-3
  • Compound CID: 5328771
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AG-494, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR.
Molecular Weight
280.28
Molecular Formula
C16H12N2O3
Targets
EGFR: 0.7 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 50 mg/mL (178.39 mM); Water: Insoluble; Ethanol: 4 mg/mL (14.27 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
AG-494 can be used to study the inhibition of EGFR tyrosine kinase in cellular signaling pathways.
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Blood Group and Lewis Antigen
Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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Dextran
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