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EGFR-HER2 inhibitor PD168393, Purity ≥98%
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Cat. No.: X24-05-ZQ632

EGFR-HER2 inhibitor PD168393, Purity ≥98%

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Synonym: 194423-15-9; PD-168393; PD 168393; EGFR-HER2 inhibitor

  • CAS Number: 194423-15-9
  • Compound CID: 4708
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Product Size
5 mg; 10 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
PD168393, soluble in DMSO and insoluble in ethanol and water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR, FGFR, Insulin Receptor, and PDGFR.
Molecular Weight
369.22
Molecular Formula
C17H13BrN4O
Targets
EGFR: 0.70 nM; FGFR: >50 μM; Insulin Receptor: >50 μM; PDGFR: >50 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 72 mg/mL (195 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
PD168393 is used to inhibit EGFR tyrosine kinase in research on cancer cell proliferation and survival pathways.
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