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EGFR-HER2 inhibitor AZ5104, Purity ≥98%

Cat. No.: X24-05-ZQ656

EGFR-HER2 inhibitor AZ5104, Purity ≥98%

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Synonym: 1421373-98-9; AZ-5104; AZ 5104; EGFR-HER2 inhibitor

  • CAS Number: 1421373-98-9
  • Compound CID: 71496460
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Product Size
10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AZ5104, soluble in DMSO and warmed ethanol and insoluble in water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR (L858R), EGFR (L861Q), ACK1, and ALK.
Molecular Weight
485.58
Molecular Formula
C27H31N7O2
Targets
EGFR (L858R): 6 nM; EGFR (L861Q): 1 nM; ACK1: 27 nM; ALK: 97 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 90 mg/mL (185.34 mM); Water: Insoluble; Warmed ethanol: 21 mg/mL (43.24 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
AZ5104 can be used to understand its activity as an EGFR inhibitor in cancer research.
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