Cat. No.: X24-05-ZQ676
EGFR-HER2 inhibitor EGFR-IN-7, Purity ≥98%
Synonym: 2267329-76-8; EGFR-IN-7; 5-Bromo-N4-[5-(dimethylphosphinyl)-6-quinoxalinyl]-N2-[2-methoxy-5-methyl-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-2,4-pyrimidinediamine; EGFR-HER2 inhibitor
- CAS Number: 2267329-76-8
- Compound CID: 138911391
Product Size
5 mg; 10 mg; 50 mg
Properties
Description
EGFR-IN-7, soluble in DMSO and insoluble in ethanol and water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR (C797S/T790M/L858R) and EGFR (WT).
Molecular Formula
C32H41BrN9O2P
Targets
EGFR (C797S/T790M/L858R): 0.218 nM; EGFR (WT): 7.92 nM
Solubility
DMSO: Insoluble; Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
EGFR-IN-7 can be used to investigate its therapeutic potential as an EGFR inhibitor in oncology research.
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